Comparative release profile of sustained release matrix tablets of verapamil HCl
نویسندگان
چکیده
منابع مشابه
ISOPTIN SR (verapamil HCl) Sustained-Release Oral Tablets
DESCRIPTION ISOPTIN SR (verapamil hydrochloride) is a calcium ion influx inhibitor (slow channel blocker or calcium ion antagonist). ISOPTIN SR is available for oral administration as light green, capsule shaped, scored, film-coated tablets containing 240 mg verapamil hydrochloride, as light pink, oval shaped, scored, film-coated tablets containing 180 mg verapamil hydrochloride, and as light v...
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The aim of this study was to develop a derivative of chitosan as pharmaceutical excipient used in sustained-release matrix tablets of poorly soluble drugs. A water-soluble quaternary ammonium carboxymethylchitosan was synthesized by a two-step reaction with carboxymethylchitosan (CMCTS), decylalkyl dimethyl ammonium and epichlorohydrin. The elemental analysis showed that the target product with...
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متن کاملOptimization of pH-independent chronotherapeutic release of verapamil HCl from three-layer matrix tablets.
The aim of this work was to evaluate and optimize formulation of three-layer matrix tablets based on xanthan gum (XG) and sodium alginate for chronotherapeutic pH-independent release of verapamil HCl (VH). Artificial neural networks (ANN) were applied in the optimization and compared with multiple linear regression (MLR). A face-centered central composite experimental design was employed with t...
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ژورنال
عنوان ژورنال: International Journal of Pharmaceutical Investigation
سال: 2013
ISSN: 2230-973X
DOI: 10.4103/2230-973x.108965